Organic letters
Palladium(II)-Catalyzed Direct C7-Acyloxylation of Indoles.
Xianyu Zhang, Jingwen Wang, Shengrong Chen, Jinghong Wu, Hongya Zhu, Ping Guo, Xintuo Yang
Published: 202610.1021/acs.orglett.5c04739
Abstract
We report a palladium-catalyzed C-H acyloxylation of indoles that achieves excellent regioselectivity at the C7 position. The synergistic combination of a methylsulfonyl directing group and a pyridone-based ligand was crucial to overriding the inhere…
Preview only. Read the full abstract at the source