Organic letters
Copper-Catalyzed Stereoselective Synthesis of Fluorinated 1,3-Dienes via Sequential Iodine-Fluorine Elimination.
Lili Zhao, Chenyang Liu, Jinghong Zhang, Jiaming Li, Cong Li, Xiaojun Zeng
Published: 202510.1021/acs.orglett.5c04718
Abstract
We report a copper-catalyzed stereoselective synthesis of fluorinated 1,3-dienes from unactivated alkenes via base-promoted sequential iodine-fluorine elimination. This protocol leverages commercially available polyfluoroalkyl iodides and β,γ-unsatur…
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