Organic letters
Cobalt-Catalyzed Regioselective Hydroxyazidation of 1,3-Dienes: Direct Access to β-Azido Alcohols.
Chi-Fan Zhu, Xiao-Jing Li, Jun-Ju Mai, Jun-Yao Guan, Mingyuan Shi, Xiasen Dong, Fener Chen
Published: 202610.1021/acs.orglett.5c04708
Abstract
A cobalt-catalyzed stereoselective 1,2-hydroxyazidation of 1,3-dienes has been developed, enabling efficient synthesis of β-azido alcohols, which retain a C═C bond for further derivatization. This protocol features a broad substrate scope, employs an…
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