Organic letters
Copper-Catalyzed Sonogashira-Type Cross-Coupling of Trifluoroalkyl Bromides with Alkynes.
Jian-Liang Yu, Ya-Wen Zuo, Yi-Gang Yang, Ruo-Xing Jin, Xi-Sheng Wang
Published: 202510.1021/acs.orglett.5c04639
Abstract
Given the significance of propargyl trifluoromethyl scaffolds in drug discovery, the development of efficient synthetic approaches for their construction remains a pressing challenge. In this work, we present copper-catalyzed Sonogashira-type cross-c…
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