Organic letters
Synthesis of C2-Iodoindoles via an Aromatic Finkelstein-Type Halide Exchange under Mild Conditions.
Yang Lv, Songren Xue, Xiang Zhang, Zhenhui Huang, Yangyang Zhang, Qi Wang, Jin Li, Bo Zhang
Published: 202610.1021/acs.orglett.5c04613
Abstract
A mild, metal-free halide exchange protocol was developed for the synthesis of C2-iodoindoles from readily available C2-chloroindoles. The transformation is carried out under ambient conditions using potassium iodide and trifluoroacetic acid and demo…
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