Organic letters
A Palladium-Catalyzed Cascade Process of 1,3-Enynes and Imines to Construct Multisubstituted Pyrrole Derivatives.
Tian-Ying Zhang, Bao-Rui Kong, Ze-Liang He, Zhi-Chao Chen, Wei Du, Ying-Chun Chen
Published: 202510.1021/acs.orglett.5c04542
Abstract
A palladium-catalyzed cascade reaction of 1,3-enynes and aldimines to efficiently access multisubstituted pyrroles is reported, proceeding in a Pd(0) π-Lewis base-mediated vinylogous addition, intramolecular central carbon N-allylation of the resulta…
Preview only. Read the full abstract at the source