Organic letters
Alkyl and Aryl Thioester Synthesis via N-Heterocyclic Carbene-Catalyzed α-Thio Aldehyde Rearrangement.
Tatsuya Fujiwara, Tsubasa Inokuma, Ken-Ichi Yamada
Published: 202610.1021/acs.orglett.5c04522
Abstract
We have developed a highly atom economic transformation to provide a thioester. The N-heterocyclic carbene-catalyzed rearrangement of α-thio aldehydes affords thioesters in good yields. This reaction exhibits a broad substrate scope and is applicable…
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