Organic letters
Synthesis of Spiroindenes via Palladium Catalysis Using Oxabicycles as Acetylene Surrogates.
Clara Jans, Armaan Grewal, Xavier Abel-Snape, Lorenzo Rizzo, Gregory J Hughes, Mark Lautens
Published: 202510.1021/acs.orglett.5c04430
Abstract
We report the palladium-catalyzed synthesis of spiroindenes using oxabicycles as acetylene surrogates. This protocol allows for the synthesis of a diverse library of heterocyclic-tethered spiroindenes. Preliminary results using enantioenriched oxabic…
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