Organic letters
Synthesis of Functionalized Isoxazoline N-Oxides by Palladium-Catalyzed Cyclization of Nitro-Tethered Alkenes.
Lei Wang, Huiwen Dong, Cangzhu Hu, Liuzhou Gao, Qiang Dai, Junliang Zhang
Published: 202610.1021/acs.orglett.5c04411
Abstract
A novel palladium-catalyzed cyclization of nitro-tethered alkenes with aryl, alkenyl, and alkynyl bromides has been developed, enabling the efficient synthesis of isoxazoline N-oxides in moderate to good yields. This transformation features a broad s…
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