Organic letters
Palladium-Catalyzed Intramolecular Hydroarylation of N-Alkynylindoles: Regioselective Synthesis of Indole-Annulated Sulfur/Phosphorus Heterocycles.
Xin-Lu Li, Bo-Xin Zhang, Ye Wang, Zhong-Wen Fan, Yan-Mei Li, Shuo-Yi Yang, Hai-Tao Yu, Yun-Long Zhao
Published: 202510.1021/acs.orglett.5c04356
Abstract
As privileged structural motifs, the efficient synthesis of multifused N-heterocycles remains highly challenging. Here, we report a palladium-catalyzed intramolecular hydroarylation of N-alkynyl indoles bearing an electron-withdrawing group at the 2-…
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