Organic letters
Photoredox-Mediated C-N Bond Cleavage Enables Synthesis of Tetra-Substituted Olefins via Reductive Radical-Polar Crossover.
Jianchen Zhang, Xiangwen Xu, Denghui Ma, Ge Liu, Fanyuanhang Yang, Yuzhen Gao, Weiping Su
Published: 202510.1021/acs.orglett.5c04351
Abstract
Synthesizing all-carbon tetra-substituted olefins is challenging due to steric hindrance. Herein, we report a concise photoinduced radical aryl migration strategy for accessing these valuable structures with excellent stereoselectivity under mild con…
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