Organic letters
Breaking the Scalability Barrier: Diversifiable Pd-Catalyzed Domino Reaction En Route to Dibenzo[b,d]azepines.
Ruoqian Fan, Yaohuang Huang, Lingchao Cai, Zhen Chen, Pavlo O Dral, Weiwei Fang
Published: 202510.1021/acs.orglett.5c04342
Abstract
Herein, we present an efficient synthesis of diverse dibenzo[b,d]azepines in high yields via Pd-catalyzed domino reactions of 2,2'-dihalobiphenyls with N-allyl alkylamines. The key to this success is in situ generation of a five-membered, chelated Pd…
Preview only. Read the full abstract at the source