Organic letters
Sodium Hypophosphite Assisted Ruthenium Catalyzed Reductive Amination under Mild Conditions.
Olesya Zvereva, Fedor S Kliuev, Natalia Lebedeva, Evgeniya Podyacheva, Evgenii Gutsul, Oleg I Afanasyev, Denis Chusov
Published: 202510.1021/acs.orglett.5c04073
Abstract
We report a catalytic method for reductive amination using sodium hypophosphite as a cheap, bulk-grade available, and environmentally friendly reductant. The use of CpRu(PPh3)2Cl allowed the reaction to proceed under mild conditions, affording produc…
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