Organic letters
Synthesis of 5-Aminooxazoles and Zwitterionic Fused Imidazolones by I2-Mediated C-H Amination.
Manman Wang, Yanliang Liu, Qingan Xiong, Pu Wang, Zhigang Yin, Junbiao Chang, Wenquan Yu
Published: 202510.1021/acs.orglett.5c04066
Abstract
Iodine-mediated C-H amination reactions of β-ketoamides with alkylamines have been developed under transition-metal-free conditions. In the presence of Na2CO3 as the base, I2-promoted annulation of β-ketoamides with benzylamines produces 5-aminooxazo…
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