Organic letters
Three-Component Cycloaddition Reaction of Aryne, Acrylate, and Imine Derivatives: Divergent Synthesis of Hexahydropyrrolo[1,2-a]quinolines and 1,4-Dihydroquinolines.
Wenbo Cai, Xin Wang, Yanyan Zhu, Chuanjun Song
Published: 202510.1021/acs.orglett.5c03900
Abstract
A novel synthetic strategy toward hexahydropyrrolo[1,2-a]quinolines and 1,4-dihydroquinolines has been demonstrated, involving aryne-enabled three-component reactions with acrylate and imine derivatives. This transition-metal-free three-component cyc…
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