Organic letters
Scalable Transannular Bromocyclization Approach to Functionalized Bis-Heterobicyclo[3.n.1]anes.
Devin P Wood, Nicolas Hernandez, Justin A Newman, Rebecca E Johnson
Published: 202510.1021/acs.orglett.5c03802
Abstract
Bicyclic, high fraction sp3 (Fsp3) building blocks have become prominent in drug discovery efforts due to the potential to improve physicochemical properties. As a result, methods to generate bicyclic rings have flourished in recent years, but there…
Preview only. Read the full abstract at the source