Organic letters
Sulfinyl-Imine-Assisted Asymmetric [3,3]-Sigmatropic Rearrangement: Generation of Tertiary and Quaternary Stereocenters.
Ganesh Karan, Susanta Bhunia, Shubham Snehil, Modhu Sudan Maji
Published: 202510.1021/acs.orglett.5c03577
Abstract
An asymmetric chemoselective allylation followed by an oxy-Cope rearrangement sequence is developed to efficiently synthesize chiral β-allylated ketoimines bearing quaternary stereocenters in excellent yields and diastereoselectivities. Besides actin…
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