Organic letters
Sc(III)-Catalyzed Carbonyl-Yne Reaction for the Diastereoselective Allene Synthesis: A Concerted Asynchronous Mechanism.
Xinya Yuan, Jiashen Yang, Shaozhong Wang
Published: 202510.1021/acs.orglett.5c03172
Abstract
The carbonyl-yne reaction, involving propargylic C-H bond cleavage for carbon-carbon bond formation, is significantly less developed than the classical Alder-ene reaction due to the linear geometry and relatively weak nucleophilicity of alkynes compa…
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