Organic letters
Enantioselective Friedel-Crafts Alkylation of Aniline Derivatives with 4-Arylidenepyrrolidine-2,3-diones Catalyzed by Chiral Cu(II) Complex Bearing Binaphthyl-Proline-Imidazoline-type Chiral Ligands.
Lei He, Mengxin Kan, Xinyu Hou, Leipeng Xue, Chao Yao, Yue-Ming Li
Published: 202510.1021/acs.orglett.5c02956
Abstract
Cu(II)-complex-catalyzed enantioselective Friedel-Crafts alkylation of aniline derivatives with 4-benzylidenepyrrolidine-2,3-dione-type electrophiles was enabled, and the desired products were obtained with up to 96% ee. Both N-mono- and N,N-dialkyla…
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