Nano lettersMicellesPaclitaxelDiffusionDrug LiberationPolyethylene Glycols
Label-Free Analysis Reveals In Vivo Premature Drug Release Governed by Diffusion from Polymeric Micelles.
Jiayi Yao, Jiefang Sun, Xinyi Wang, Haoran Wang, Yuqi Liu, Mingyang Zhao, Xiangjun Meng, Jingkai Gu
Published: 202510.1021/acs.nanolett.5c05381
Abstract
Premature drug release in the bloodstream significantly limits the clinical use of polymeric micelles (PMs). However, whether this release results primarily from drug diffusion or micelle dissociation is still unclear because current techniques canno…
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