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Synergistic Nucleus-Targeting Photodynamic Therapy and DNA Repair Inhibition to Activate Innate and Adaptive Antitumor Immunity for Amplifying Photoimmunotherapy.
Yunxue Xu, Wenlong Zeng, Renfa Liu, Zhifei Dai, Desheng Sun
Published: 202510.1021/acs.nanolett.5c04141
Abstract
Photodynamic therapy (PDT) has received increasing attention because it can induce immunogenic cell death (ICD) and activate the STING pathway. However, the immune response induced by PDT is limited by its poor DNA damage, due to random intracellular…
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