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A Synthetic Liposome Nanoparticle Vaccine Platform for Broad-Spectrum Vaccine Design.
Mo Zhang, Zihan Gao, Sheng Feng, Xun Wang, Huaiyu Wang, Chumeng Yang, Xiaolei Lin, Zhiqiang Xu, Nan Zhang, Yiyang Li, Haochen Tian, Ningyi Jin, Bin Yu, Pengfei Wang, Chang Li
Published: 202510.1021/acs.nanolett.5c03021
Abstract
Emerging viruses such as SARS-CoV-2 and HIV-1 pose major challenges for traditional vaccines due to their rapid mutation and immune evasion. Here, we present a modular liposomal nanoparticle (LNP) vaccine platform integrating trimeric immunogens and…
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