Molecular pharmaceutics
Pharmacokinetic Optimization of Radiocopper-Based Theranostic Pretargeting.
Mike A Cornejo, Zachary V Samuels, Gina Dehlavi, Lukas Carter, Wei-Siang Mark Kao, Emilia Strugala, Brian M Zeglis
Published: 202610.1021/acs.molpharmaceut.5c01512
Abstract
In vivo pretargeting offers a strategy to improve nuclear imaging and radiopharmaceutical therapy by increasing tumor-to-background activity concentration ratios and decreasing radiation burden to healthy tissues. One particularly promising approach…
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