Molecular pharmaceuticsAnimalsTrastuzumabHumansMiceRadiopharmaceuticals
Supramolecular Chemistry Enables Radiolabeling of Proteins under Mild Conditions.
Romane Vizier, Milou Boswinkel, Mathieu Moreau, Johan Faivre, Manon Carrierre, Maxime Cheveau, Sophie Poty, Franck Denat, Sanne A M van Lith, Victor Goncalves
Published: 202510.1021/acs.molpharmaceut.5c01339
Abstract
Monoclonal antibodies have proven to be highly effective for in vivo targeting in nuclear medicine applications. However, typical radiolabeling methods, for PET/SPECT imaging and targeted radionuclide therapy, often require conditions that may affect…
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