Molecular pharmaceuticsTemozolomideSilicon DioxideAnimalsGliomaNanoparticles
Functionalized Mesoporous Silica@Mercuric Oxide Core-Shell Nanoparticles Loaded with Temozolomide for Targeted Treatment of Glioma.
Yu Zhao, Zhiwei Shi, Huan Shi, Jing Wang, Han Wang, Fu Zhu, Yu Gao, Ying Liu, Chao Wu
Published: 202610.1021/acs.molpharmaceut.5c01254
Abstract
In this research, we synthesized mesoporous silica@mercury oxide nanoparticles featuring a core-shell structure (MSM) for the nasal delivery of Temozolomide (TMZ) to achieve targeted treatment of glioma. Nasal administration can bypass the first-pass…
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