Molecular pharmaceuticsHumansApoptosisKB CellsFolic AcidSignal Transduction
Signaling and Mechanistic Insights into Folate Binding Protein-Induced Cytotoxicity in KB Cancer Cells.
Hajar Samadian, Jennifer M Dyson, Rujula Pradeep, Manuel Rosa-Garrido, Mark M Banaszak Holl
Published: 202610.1021/acs.molpharmaceut.5c00966
Abstract
A recent study on folate binding protein (FBP), the soluble form of a folate receptor (FR), revealed surprising inhibition of in vivo growth of KB cell-derived xenograft tumors in mice and the induction of in vitro caspase-mediated apoptosis in KB, H…
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