Molecular pharmaceuticsPaliperidone PalmitateEmulsionsAnimalsAdministrationIntranasal
Optimization and Evaluation of Functionally Engineered Paliperidone Nanoemulsions for Improved Brain Delivery via Nasal Route.
Niserga D Sawant, Pratima A Tatke, Namita D Desai
Published: 202510.1021/acs.molpharmaceut.5c00786
Abstract
Paliperidone, a second-generation antipsychotic approved by USFDA for schizophrenia, exhibits low aqueous solubility and high permeability, classifying it under BCS II. The present study focused on brain delivery of paliperidone through the nasal rou…
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