Molecular pharmaceuticsFreeze DryingHigh-Throughput Screening AssaysMicrobial ViabilityExcipientsTrehalose
A High-Throughput Microbial Viability Assay to Evaluate Lyoprotectants for Live Biotherapeutic Products.
Haixi Cui, Jonathan T Feng, Sonali Kumari, Hua Yu, Di Yu, Hanping Feng, Stephen W Hoag
Published: 202510.1021/acs.molpharmaceut.5c00557
Abstract
Many cell-based therapies, such as live biotherapeutic products (LBPs), require preservation of cell viability during manufacturing, transportation, and storage before being delivered to patients. Although lyophilization is a common strategy to impro…
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