Molecular pharmaceuticsSolubilityFlavonoidsCrystallizationX-Ray DiffractionAnimals
Chrysin Cocrystals: Prediction, Preparation, Characterization, and In Vitro/In Vivo Evaluation.
Baoxi Zhang, Yifei Xie, Weiwen Ji, Li Zhang, Qi Wang, Shiying Yang, Dezhi Yang, Yang Lu
Published: 202610.1021/acs.molpharmaceut.5c00397
Abstract
In this study, crystal engineering was employed to enhance the solubility and druggability of Chrysin (CHR). Four nitrogen heterocyclic compounds, including piperazine (PIP), 4,4'-bipyridine (BIP), imidazole (IMI), and sophoridine (SOP), were investi…
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