Langmuir : the ACS journal of surfaces and colloidsalpha-DefensinsCathelicidinsHumansAntimicrobial Cationic PeptidesAmino Acid Sequence
Single Amino Acid Modulates Antimicrobial Peptide Cooperativity between LL-37 and HNP1.
Ariane M Schwitter, Takashi Yasuda, Xiang Li, Kaori Sugihara
Published: 202610.1021/acs.langmuir.5c04387
Abstract
Antimicrobial peptides (AMPs) are promising agents against infections caused by multidrug-resistant bacteria. Notably, the human AMPs LL-37 and α-defensin (HNP1) exhibit a cooperative effect, synergistically killing bacteria while reducing host cytot…
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