Journal of proteome research
Toward Proteomic-Based Prediction of Ex Vivo Platinum Sensitivity in Ovarian Cancer Ascitic Cellular Aggregates: A Pilot Study.
Jack Scanlan, Parul Mittal, Noor A Lokman, Martin K Oehler, Peter Hoffmann, Manuela Klingler-Hoffmann
Published: 202510.1021/acs.jproteome.5c00771
Abstract
The accumulation of malignant ascites in the peritoneal cavity is a hallmark of high-grade serous ovarian cancer (HGSC). This fluid contains three-dimensional multicellular aggregates known as spheroids, which contribute to chemoresistance and are an…
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