Journal of proteome researchHumansFemaleOvarian NeoplasmsTumor Suppressor Protein p53Drug Resistance
Multilayered Regulatory Dynamics of p53 Mutations and Platinum Resistance in Ovarian Cancer.
Liling Hu, Hanchen Zou, LvYing Peng, Fan Li, Danya Liu, Jiangli Lu, Yuying Li, Chris Zhiyi Zhang, Qiu-Hong Tian
Published: 202610.1021/acs.jproteome.5c00657
Abstract
TP53 mutation-driven gene expression programs define oncogenic phenotypes. While extensive studies have concentrated on the transcriptome and proteome, post-transcriptional processes, particularly translational variation, remain underexplored. This s…
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