The journal of physical chemistry lettersAnimalsSpidersBombyxSilkProtein Multimerization
Distinct Dimerization Mechanisms in Silkworm and Spider Silk Proteins Revealed by Mass Photometry.
Hannah R Johnson, Herman K Dhaliwal, Nino Makasarashvili, John Malki, Fernando Vasquez, Daniel Villarreal, Lado Shapakidze, Gregory P Holland, Rees F Garmann
Published: 202510.1021/acs.jpclett.5c02335
Abstract
We apply mass photometry to measure the mass distributions of individual protein assemblies in native silk dopes from Bombyx mori silkworms and Latrodectus hesperus spiders. In both systems, we find that protein dimers dominate, but with distinct sta…
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