The Journal of organic chemistry
Ni-Catalyzed Cyclotrimerization of Unactivated Internal Alkynes: Ligand-Dependent Regioselectivity.
Ahyeon Cho, Jaehan Bae, Eun Jin Cho
Published: 202510.1021/acs.joc.5c02666
Abstract
A nickel-catalyzed [2 + 2 + 2] cyclotrimerization of unactivated internal alkynes is presented, enabling regioselective access to fully substituted benzene derivatives through ligand control. The transformation proceeds under additive-free conditions…
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