The Journal of organic chemistry
Diketone-Enabled Regioselective Cobalt-Catalyzed C-H/N-H Activation with Alkyl Alkynes.
Jia-Wei Li, Yu-Yan Tan, Xiao-Hong Chen, Yan-Jie Liu, Wen-Jie Shi, Panjie Hu, Song-Xue Luo, Jia-Le Song, Chen Chen, Yingxi Wang, Yue-Jin Liu
Published: 202610.1021/acs.joc.5c02578
Abstract
Annulation of alkynes with C-H/N-H bonds is a green and efficient method for constructing lactams. Controlling the regioselectivity of unsymmetric alkynes, especially alkyl-substituted alkynes, remains challenging. Herein, we report a regioselective…
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