The Journal of organic chemistry
A Tandem Strategy: Wolff Rearrangement/Staudinger [2+2] Cycloaddition via Metal Carbenes for the Synthesis of Spiro[azetidine-3,3'-benzofuran]-2-ones.
Ju Zhai, Li Pu, Dan Liu, Hejiang Luo, Rong-Tao Li
Published: 202610.1021/acs.joc.5c02566
Abstract
The spiro[azetidine-3,3'-benzofuran]-2-one motif represents an important yet underexplored class of spirocyclic β-lactams, making the development of an efficient synthetic route to access this scaffold highly desirable. Herein, we report a concise ta…
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