The Journal of organic chemistry
P(NMe2)3-Mediated Reductive (4 + 1) Annulation Reaction of Isatins with Oxindole-Derived α,β-Unsaturated Imines and Diastereoselective Synthesis of 2,3-Di(spirooxindolyl)pyrrolines.
Fangna Sun, Pei-Jie Huang, Lin Liu, Jiesi Luo, Chang-Jiang Yang, Zhengjie He
Published: 202510.1021/acs.joc.5c02507
Abstract
Herein, we report a P(NMe2)3-mediated (4 + 1) annulation reaction between substituted isatins and oxindole-derived α,β-unsaturated imines. This method facilitates the diastereoselective synthesis of a variety of structurally diverse 2,3-di(spirooxind…
Preview only. Read the full abstract at the source