The Journal of organic chemistry
Tandem Hydroxybenzothiophene Synthesis Mediated by LiN(SiMe3)2.
Yuanyun Gu, Kangyu Yin, Yan-En Wang, Yanqing Ji, Yaqi Yuan, Dan Xiong, Jianyou Mao
Published: 202510.1021/acs.joc.5c02484
Abstract
Benzothiophenes are pivotal heterocycles in pharmaceuticals due to their broad biological activities. Existing methods often require harsh conditions, toxic reagents, or expensive transition metals. Herein, we report a one-pot transition-metal-free s…
Preview only. Read the full abstract at the source