The Journal of organic chemistry
Copper-Catalyzed Synthesis of Tetrasubstituted Olefins with Bicyclo[1.1.0]butanes and α-Diazo-Esters.
Qing-Yi Ru, Jia-Heng Li, Hu Tian, Liang Yin
Published: 202510.1021/acs.joc.5c02465
Abstract
BCBs (bicyclo[1.1.0]butanes) serve as useful building blocks in organic synthesis due to their unique reactivity caused by the ring-strain. Herein, a copper-catalyzed olefination with BCBs and α-diazo-esters is disclosed, which generates tetrasubstit…
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