The Journal of organic chemistry
Photoinduced Palladium-Catalyzed Decarboxylative Radical Cross Coupling Reaction of Secondary Amides with α-Keto Acids to Access Pharmaceutically Relevant Imides.
Rageshree Dash, Asish Kumar Sahoo, Swastik Kumar Behera, Chandra Shekhar Nishad, Kamaldeep Kaur, Ashish Kumar, Sahil Mondal, Biplab Banerjee
Published: 202510.1021/acs.joc.5c02412
Abstract
Developing sustainable methods for C-N bond formation is crucial for drug discovery. Visible-light-induced palladium-catalyzed decarboxylative radical cross coupling of isoxazole carboxamides with α-keto acids is developed for the synthesis of pharma…
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