The Journal of organic chemistry
Synthesis of Indenopiperidinone Derivatives Achieved through the Aza-Semipinacol-Type Rearrangement of Iodobenzomorphanones.
Magdalena M Lubowicz, Tomasz J Idzik, Łukasz Struk, Jacek G Sośnicki
Published: 202510.1021/acs.joc.5c02343
Abstract
The synthesis of 2,4,4a,9-tetrahydro-3H-indeno[2,1-c]pyridin-3-ones 7 is achieved through the aza-semipinacol-type rearrangement of readily available iodobenzomorphanones when treated with silver salts. A comprehensive study was performed on the opti…
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