The Journal of organic chemistry
Automated Synthesis of NET-Targeted PET Tracers [18F]4F-mHPG and [18F]3F-pHPG through Photocatalyzed 18F-Deoxyfluorination.
Yarong Cao, Yang Xie, Lili Pan, Yueqi Wang, Honghai Yin, Mingxing Hu, Xiaoai Wu, Wei Chen
Published: 202510.1021/acs.joc.5c02276
Abstract
The NET-targeted radiotracers [18F]4F-mHPG and [18F]3F-pHPG have demonstrated promising clinical applications; however, the preparation of these tracers remains challenging. Herein, we report an improved synthesis protocol that enables the efficient…
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