The Journal of organic chemistry
A Synthetic Route to Hexahydroimidazoquinolines via Ring-Opening Cyclization of Aziridines with Tetrahydroquinoline.
Poulami Mandal, Vashundhra Sharma, Amit K Sharma, Satysen Yadav, Manas K Ghorai
Published: 202510.1021/acs.joc.5c02155
Abstract
An efficient synthetic route to 1,2,3,3a,4,5-hexahydroimidazo[1,2-a] quinolines in up to 70% yields with high stereoselectivity (dr up to 89:11) via Lewis acid-catalyzed SN2-type ring opening of activated aziridines with tetrahydroquinoline, followed…
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