The Journal of organic chemistry
The Sulfenylation of Pyrazolones with Heterocyclic Thiols or Disulfides in Water and Application to DNA-Compatible Chemistry.
Dulin Kong, Wenyan Wei, Senyao Zheng, Junchao Lu, Xiaolin Cui, Guiwei Yao, Xia Zhong, Xun Chen, Guangkuan Zhao
Published: 202510.1021/acs.joc.5c02096
Abstract
A practical and efficient method for synthesizing 4-sulfenylpyrazol-5-ol compounds has been established through a hydrogen peroxide (H2O2)-promoted cross-dehydrogenative coupling (CDC) reaction between heterocyclic thiols and pyrazolones in water. Th…
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