The Journal of organic chemistry
Base-Catalyzed Lossen Rearrangement: Modular Synthesis of α-Fluoroamides.
Chong Li, Lin-Yuan Song, Ya-Ting Cao, Shu-Yu Hou, Yi-Fei Liu, Xiong-Feng Cai, Shu-Chen Zhou, Hai Yang, Feng Li
Published: 202510.1021/acs.joc.5c02026
Abstract
Herein, we have developed a cascade reaction, which constructs C-N, C-C, and C-F bonds in a one-pot process through a base-catalyzed Lossen rearrangement of dioxazolones. The key to the success of this process lies in utilizing the base-catalyzed Los…
Preview only. Read the full abstract at the source