The Journal of organic chemistryPeptidesAmino AcidsAzepinesModelsMolecular
Conformational Analysis of Helical Peptides Incorporating Azepane-Based β-Amino Acids Prepared by an Ultrasound-Assisted Method.
Ingyu Han, Chae Na Lim, Soo Hyuk Choi
Published: 202510.1021/acs.joc.5c01530
Abstract
We report the synthesis of cis-5-aminoazepane-4-carboxylic acid (cis-AAzC) and its conformational behavior in nontraditional helical peptides. An ultrasound-assisted reductive amination method improves chemical yields and reduces solvent usage compar…
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