The Journal of organic chemistry
α-Olefination of Nitriles: Base-Promoted Ring-Opening Coupling of Nitriles and Chromone.
Di Wu, Sheng Tao, Tao Wang, Jun-Yuan Tang, Fei Chen, Zhi-Hong Du, Chun-Bo Bo, Min Li, Bin Dai, Ning Liu
Published: 202510.1021/acs.joc.5c01471
Abstract
A new strategy for base-promoted ring-opening coupling reaction between nitriles and chromones for the synthesis of α-olefins was developed. This method demonstrates significant advantages, including high atomic economy, metal-free, air atmosphere, s…
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