Substrate-Directed Annulative-Sulfonylation/Desulfonylation Cascade Using (E)-β-Iodovinyl Sulfones: A Diverse Approach for the Synthesis of Imidazo[1,2-a]pyridines with Sulfone Motifs.

The 3-aryl-imidazo[1,2-a]pyridines are among the most promising molecular frameworks in drug discovery and development; however, their sulfonyl analogues remain largely underexplored. In this study, we report a base-mediated annulative-sulfonylation…

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