The Journal of organic chemistry
Cobalt-Catalyzed Amide Bond Formation from Esters and Amines.
Xiao-Bin Li, Xiao-Xiong Lv, Fei Chen, Zhi-Hong Du, Chun-Bo Bo, Min Li, Donghui Wei, Ning Liu
Published: 202510.1021/acs.joc.5c01276
Abstract
Amide bonds are ubiquitously present in natural products and drug molecules. Traditional methods for constructing amide bonds rely on stoichiometric activating reagents, often leading to the generation of substantial waste. Therefore, the development…
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