The Journal of organic chemistry
Electrochemical Trifluoromethylation/Cyclization of N'-Arylidene-N-acryloyltosylhydrazides for the Synthesis of CF3-Substituted Pyrazolones.
Yu Xia, Wenlong Xu, Xinquan Wu, Tingting Yin, Shaofeng Wu, Ziren Chen, Bin Wang, Yonghong Zhang, Chenjiang Liu
Published: 202510.1021/acs.joc.5c01197
Abstract
Herein, a mild and efficient synthesis of pyrazolones is disclosed through a sustainable electrochemical method. This electrolysis relied on cascade trifluoromethylation/cyclization by using CF3SO2Na as a trifluoromethyl source, which occurred direct…
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